Á¤ÅºÍ×°ì¸üÀ¸Ï«Æ¯Áê¤Ï£¶Æü¤Î³ÕµÄ¸å²ñ¸«¤Ç¡¢Ìô³²£Ã·¿´Î±êÂкö¤Ë¤Ä¤¤¤Æ¡¢¡Öºâ̳¾Ê¤äÁí̳¾Ê¤ÈÁêÃ̤·¤Ê¤¯¤Æ¤Ï¤¤¤±¤Ê¤¤¤¬¡¢Êý¸þ¤È¤·¤Æ¤Ï¸¡ºº¤Î̵ÎÁ²½¤ò¹Í¤¨¤Æ¤ª¤ê¡¢¤¶¤Ã¤È·×»»¤¹¤ì¤Ð¡¢£²£µ²¯±ß¤ÎÈñÍѤ¬¤«¤«¤ë¤È»×¤Ã¤Æ¤¤¤ë¡×¤È½Ò¤Ù¡¢´Î±ê¤Î´¶À÷¤¬¿´ÇۤʿͤòÂоݤˡ¢Áᤱ¤ì¤ÐǯÌÀ¤±¤ò¤á¤É¤Ë°åÎŵ¡´Ø¤Ê¤É¤Ç¤Î̵ÎÁ¸¡¿Ç¤ò¼Â»Ü¤·¤¿¤¤°Õ¸þ¤ò¼¨¤·¤¿¡£
Á¤Åº»á¤ÏÈñÍÑÉéô¤Î´ü´Ö¤Ï£±Ç¯´Ö¤Î»þ¸ÂŪ¤ÊÁ¼ÃÖ¤òÁÛÄꤷ¤Æ¤ª¤ê¡¢¡Ö¤¤¤Ä¸¡¿Ç¤Ë¹Ô¤Ã¤Æ¤¤¤¤¤È¤¤¤¦¤Î¤Ç¤Ï¤Ê¤¯¡¢´ü´Ö¤òÄê¤á¤ë¤³¤È¤Ç¡¢¸¡¿Ç¤òÁá¤á¤ë¸ú²Ì¤Ë¤â¤Ê¤ë¤È»×¤¦¡£´Î±ê¥¦¥¤¥ë¥¹¤ò»ý¤Ã¤Æ¤¤¤ë¿Í¤âÁ᤯ȯ¸«¤Ç¤¤ë¡×¤È½Ò¤Ù¡¢Ã»´ü´Ö¤Ç¤Î¼õ¿ÇΨ¤Î¸þ¾å¤äÁá´üȯ¸«¤Î¸ú²Ì¤Ë´üÂÔ¤ò¹þ¤á¤¿¡£
¸½ºß¤Ï¡¢ÃÏÊý¼«¼£ÂΤˤè¤Ã¤Æ¸¡ºº¤¬ÌµÎÁ¤È¤Ê¤ë¾ì¹ç¤â¤¢¤ë¤¬¡¢°ìÉô¼«¼£ÂΤä°åÎŵ¡´Ø¤Ç¤ÏÍÎÁ¤È¤Ê¤Ã¤Æ¤¤¤ë¡£¹ñ¤Ï³Æ´ë¶È¤Î·ò¹¯Êݸ±Áȹç¤Ë£´£°ºÐ°Ê¾å¤Î¿Í¤ËÂФ·¤Æ¸¡ºº¤ò¹Ô¤¦¤è¤¦¸Æ¤Ó³Ý¤±¤Æ¤¤¤ë¤¬¡¢¼Â»Ü¤·¤Æ¤¤¤ë¤Î¤ÏÌó£³³ä¤Ë¤È¤É¤Þ¤Ã¤Æ¤¤¤ë¡£
(´Î±ê¤Î¸¡¿Ç̵ÎÁ²½¡¢Á¤Åº¸üÏ«Á꤬»ä°Æ)
C·¿´Î±ê¤È¤Ï¡¢C·¿´Î±ê¥¦¥¤¥ë¥¹¤Ë´¶À÷¤¹¤ë¤³¤È¤Çȯ¾É¤¹¤ë¥¦¥¤¥ë¥¹À´Î±ê¤Î°ì¼ï¤Ç¤¹¡£·ì±Õ(·ì±ÕÀ½ºÞ ´Þ¤à)¤¬¼ç¤Ê´¶À÷·ÐÏ©¤Ç¡¢¤«¤Ä¤Æ¤ÏÍ¢·ì¤Ë¤è¤ë´¶À÷¤¬Â¿¤«¤Ã¤¿¤Ç¤¹¤¬¡¢ºÇ¶á¤Ç¤Ï¸¡ººÂÎÀ©¤¬³ÎΩ¤·¤¿¤¿¤á¡¢¤Û¤È¤ó¤É¿Ë»É¤·»ö¸Î¤Ê¤É¤¬ÌäÂê¤È¤Ê¤Ã¤Æ¤¤¤Þ¤¹¡£
C·¿´Î±ê¥¦¥¤¥ë¥¹¤Ï¡¢´¶À÷¤·¤Æ¤â´Î±ê¤òȯ¾É¤·¤Ê¤¤¤³¤È¤¬¤¢¤ê¤Þ¤¹¡£¤³¤ì¤ÏHCV¤Ë´¶ºî¤µ¤ì¤¿ºÙ˦¾ã³²ÀT¥ê¥ó¥Ñµå¤¬¡¢´ÎºÙ˦¤ò½ý³²¤¹¤ë¤¿¤á¤Ç¤Ï¤Ê¤¤¤«¤È¹Í¤¨¤é¤ì¤Æ¤¤¤Þ¤¹¡£µÞÀ´Î±êȯ¾É¸å¤âALT¤¬¹âÃͤòÊݤÁ¡¢HCV RNA¤âÍÛÀ¤Î¤Þ¤Þ»ý³¤·¤ÆËýÀ´Î±ê¤Ë°Ü¹Ô¤¹¤ëÎ㤬¿¤¤¤È¤¤¤ï¤ì¤Æ¤¤¤Þ¤¹¡£
C·¿´Î±ê¥¦¥¤¥ë¥¹¤Ë´¶À÷¤·¤Æ¤¤¤ë¤«¤É¤¦¤«¤Ï¡¢°Ê²¼¤Î¤è¤¦¤Ê¸¡ºº¤ò¹Ô¤¦¤³¤È¤Ç¿ÇÃǤǤ¤Þ¤¹¡£
Á¤Åº»á¤ÏÈñÍÑÉéô¤Î´ü´Ö¤Ï£±Ç¯´Ö¤Î»þ¸ÂŪ¤ÊÁ¼ÃÖ¤òÁÛÄꤷ¤Æ¤ª¤ê¡¢¡Ö¤¤¤Ä¸¡¿Ç¤Ë¹Ô¤Ã¤Æ¤¤¤¤¤È¤¤¤¦¤Î¤Ç¤Ï¤Ê¤¯¡¢´ü´Ö¤òÄê¤á¤ë¤³¤È¤Ç¡¢¸¡¿Ç¤òÁá¤á¤ë¸ú²Ì¤Ë¤â¤Ê¤ë¤È»×¤¦¡£´Î±ê¥¦¥¤¥ë¥¹¤ò»ý¤Ã¤Æ¤¤¤ë¿Í¤âÁ᤯ȯ¸«¤Ç¤¤ë¡×¤È½Ò¤Ù¡¢Ã»´ü´Ö¤Ç¤Î¼õ¿ÇΨ¤Î¸þ¾å¤äÁá´üȯ¸«¤Î¸ú²Ì¤Ë´üÂÔ¤ò¹þ¤á¤¿¡£
¸½ºß¤Ï¡¢ÃÏÊý¼«¼£ÂΤˤè¤Ã¤Æ¸¡ºº¤¬ÌµÎÁ¤È¤Ê¤ë¾ì¹ç¤â¤¢¤ë¤¬¡¢°ìÉô¼«¼£ÂΤä°åÎŵ¡´Ø¤Ç¤ÏÍÎÁ¤È¤Ê¤Ã¤Æ¤¤¤ë¡£¹ñ¤Ï³Æ´ë¶È¤Î·ò¹¯Êݸ±Áȹç¤Ë£´£°ºÐ°Ê¾å¤Î¿Í¤ËÂФ·¤Æ¸¡ºº¤ò¹Ô¤¦¤è¤¦¸Æ¤Ó³Ý¤±¤Æ¤¤¤ë¤¬¡¢¼Â»Ü¤·¤Æ¤¤¤ë¤Î¤ÏÌó£³³ä¤Ë¤È¤É¤Þ¤Ã¤Æ¤¤¤ë¡£
(´Î±ê¤Î¸¡¿Ç̵ÎÁ²½¡¢Á¤Åº¸üÏ«Á꤬»ä°Æ)
C·¿´Î±ê¤È¤Ï¡¢C·¿´Î±ê¥¦¥¤¥ë¥¹¤Ë´¶À÷¤¹¤ë¤³¤È¤Çȯ¾É¤¹¤ë¥¦¥¤¥ë¥¹À´Î±ê¤Î°ì¼ï¤Ç¤¹¡£·ì±Õ(·ì±ÕÀ½ºÞ ´Þ¤à)¤¬¼ç¤Ê´¶À÷·ÐÏ©¤Ç¡¢¤«¤Ä¤Æ¤ÏÍ¢·ì¤Ë¤è¤ë´¶À÷¤¬Â¿¤«¤Ã¤¿¤Ç¤¹¤¬¡¢ºÇ¶á¤Ç¤Ï¸¡ººÂÎÀ©¤¬³ÎΩ¤·¤¿¤¿¤á¡¢¤Û¤È¤ó¤É¿Ë»É¤·»ö¸Î¤Ê¤É¤¬ÌäÂê¤È¤Ê¤Ã¤Æ¤¤¤Þ¤¹¡£
C·¿´Î±ê¥¦¥¤¥ë¥¹¤Ï¡¢´¶À÷¤·¤Æ¤â´Î±ê¤òȯ¾É¤·¤Ê¤¤¤³¤È¤¬¤¢¤ê¤Þ¤¹¡£¤³¤ì¤ÏHCV¤Ë´¶ºî¤µ¤ì¤¿ºÙ˦¾ã³²ÀT¥ê¥ó¥Ñµå¤¬¡¢´ÎºÙ˦¤ò½ý³²¤¹¤ë¤¿¤á¤Ç¤Ï¤Ê¤¤¤«¤È¹Í¤¨¤é¤ì¤Æ¤¤¤Þ¤¹¡£µÞÀ´Î±êȯ¾É¸å¤âALT¤¬¹âÃͤòÊݤÁ¡¢HCV RNA¤âÍÛÀ¤Î¤Þ¤Þ»ý³¤·¤ÆËýÀ´Î±ê¤Ë°Ü¹Ô¤¹¤ëÎ㤬¿¤¤¤È¤¤¤ï¤ì¤Æ¤¤¤Þ¤¹¡£
C·¿´Î±ê¥¦¥¤¥ë¥¹¤Ë´¶À÷¤·¤Æ¤¤¤ë¤«¤É¤¦¤«¤Ï¡¢°Ê²¼¤Î¤è¤¦¤Ê¸¡ºº¤ò¹Ô¤¦¤³¤È¤Ç¿ÇÃǤǤ¤Þ¤¹¡£
¤Þ¤º¤Ï¡¢È¯¾ÉÁ°6¥ö·î´Ö¤ËÍ¢·ì¡¢Ãí¼Í¡¢¼ê½Ñ¡¢¿Ë»É¤·»ö¸Î¤Ê¤É¤Î´¶À÷¤Î¸¶°ø¤È¤Ê¤ê¤¦¤ë¤³¤È¤¬¤¢¤Ã¤¿¤«¤É¤¦¤«¤ò³Îǧ¤·¤Þ¤¹¡£
¸½ºß¤Ç¤Ï¡¢
¤Î3¤Ä¤ÎÊýË¡¤òŬµ¹ÁȤ߹ç¤ï¤»¤ÆȽÃǤ¹¤ëÊýË¡¤¬°ìÈ̤˺ÎÍѤµ¤ì¤Æ¤¤¤Þ¤¹¡£
HCV¹³ÂÎÍÛÀ¤Î¿Í¤ÎÃæ¤Ë¤Ï¡¢¡¸½ºß¥¦¥¤¥ë¥¹´¶À÷¤·¤Æ¤¤¤ë¿Í(HCV¥¥ã¥ê¥¢)¤È¢HCV¤Ë´¶À÷¤·¤¿¤¬¼£¤Ã¤Æ¤·¤Þ¤Ã¤¿¿Í(´¶À÷´û±ý¼Ô)¤È¤¬´Þ¤Þ¤ì¤ë¤¿¤á¡¢¤³¤ì¤ò¶èÊ̤¹¤ë¤¿¤á¤ËHCV¹³¸¶¸¡ºº¤ª¤è¤ÓHCV³Ë»ÀÁýÉý¸¡ºº¤òŬµ¹ÁȤ߹ç¤ï¤»¤ÆȽÃǤ·¤Þ¤¹¡£
C·¿´Î±ê¥¦¥¤¥ë¥¹¤Î¹½Â¤¤Ï¡¢¥¦¥¤¥ë¥¹¤Î°äÅÁ»Ò¡¢°äÅÁ»Ò¤òÊñ¤ó¤Ç¤¤¤ë¥³¥¢¡¢³°Â¦¤òÊñ¤à³°³Ì¤«¤éÀ®¤êΩ¤Ã¤Æ¤¤¤Þ¤¹¡£HCV¥³¥¢¹³¸¶¸¡ºº¤Ï¡¢C·¿´Î±ê¥¦¥¤¥ë¥¹(HCV)¤Î¥³¥¢Éôʬ¤Î¥¿¥ó¥Ñ¥¯¤òľÀܸ¡½Ð¤·¤Þ¤¹¡£°ìÊý¡¢³Ë»ÀÁýÉý¸¡ºº¤Ï¡¢¥¦¥¤¥ë¥¹¤ò¹½À®¤¹¤ë³Ë»À¤Î°ìÉô¤òÌó1²¯ÇܤËÁýÉý¤·¤Æ¥¦¥¤¥ë¥¹¤ÎÍ̵¤ò¸¡½Ð¤·¤Þ¤¹¡£
¤Ç¤¹¤Î¤Ç¡¢
1¡¥HCV¹³Âθ¡ºº¤Ç¹âÎϲÁ¢ª´¶À÷¤Î²ÄǽÀ¤¬¹â¤¤¡£
2. HCV¹³Âθ¡ºº¤ÇÃæÎϲÁ¢ªHCV¹³¸¶¸¡ºº¢ªÍÛÀ¤Ê¤é´¶À÷¤Î²ÄǽÀ¤¬¹â¤¤¡£
3¡¥HCV¹³Âθ¡ºº¤ÇÄãÎϲÁ¢ªHCV¹³¸¶¸¡ºº¤Ç±¢À¢ªHCV³Ë»ÀÁýÉý¸¡ºº¢ªÍÛÀ¤Ê¤é´¶À÷¤Î²ÄǽÀ¤¬¹â¤¤¡£
4.HCV¹³Âθ¡ºº¤Ç±¢À¢ªHCV¤Ë´¶À÷¤·¤Æ¤¤¤Ê¤¤²ÄǽÀ¤¬¹â¤¤
¤È¤¤¤Ã¤¿¤³¤È¤¬¸¡ºº¤Çʬ¤«¤ê¤Þ¤¹¡£
À§Èó¤È¤âÈï³²¼ÔµßºÑ¤Î¤¿¤á¤Ë¡¢¼Â¸½²½¤·¤ÆÍߤ·¤¤¤È»×¤ï¤ì¤Þ¤¹¡£
¡Ú´ØÏ¢µ»ö¡Û
HCV¤Ë¤è¤ëËýÀ´Î±ê¤¬´Î¡¤¬¤ó¤Ë¿Ê¹Ô¤¹¤ë»ÅÁȤߤò²òÌÀ
Éã¿Æ¤Î°é»ù¤¬Áý¤¨¤Æ¡¢B·¿´Î±ê¤ÎÉã»Ò´¶À÷¤¬Áý²Ã
¸½ºß¤Ç¤Ï¡¢
1)·ì±ÕÃæ¤ÎHCV¹³ÂΤÎÎÌ(HCV¹³ÂβÁ)¤ò¬Äꤹ¤ë¤³¤È(HCV¹³Âθ¡ºº¡Ë
2)HCV¤Î¥³¥¢¹³¸¶¤ò¸¡½Ð¤¹¤ë¤³¤È¡ÊHCV¹³¸¶¸¡ºº¡Ë
3)³Ë»ÀÁýÉý¸¡ºº¤Ë¤è¤êHCV¤Î°äÅÁ»Ò¤ò¸¡½Ð¤¹¤ë¤³¤È
¤Î3¤Ä¤ÎÊýË¡¤òŬµ¹ÁȤ߹ç¤ï¤»¤ÆȽÃǤ¹¤ëÊýË¡¤¬°ìÈ̤˺ÎÍѤµ¤ì¤Æ¤¤¤Þ¤¹¡£
HCV¹³ÂÎÍÛÀ¤Î¿Í¤ÎÃæ¤Ë¤Ï¡¢¡¸½ºß¥¦¥¤¥ë¥¹´¶À÷¤·¤Æ¤¤¤ë¿Í(HCV¥¥ã¥ê¥¢)¤È¢HCV¤Ë´¶À÷¤·¤¿¤¬¼£¤Ã¤Æ¤·¤Þ¤Ã¤¿¿Í(´¶À÷´û±ý¼Ô)¤È¤¬´Þ¤Þ¤ì¤ë¤¿¤á¡¢¤³¤ì¤ò¶èÊ̤¹¤ë¤¿¤á¤ËHCV¹³¸¶¸¡ºº¤ª¤è¤ÓHCV³Ë»ÀÁýÉý¸¡ºº¤òŬµ¹ÁȤ߹ç¤ï¤»¤ÆȽÃǤ·¤Þ¤¹¡£
C·¿´Î±ê¥¦¥¤¥ë¥¹¤Î¹½Â¤¤Ï¡¢¥¦¥¤¥ë¥¹¤Î°äÅÁ»Ò¡¢°äÅÁ»Ò¤òÊñ¤ó¤Ç¤¤¤ë¥³¥¢¡¢³°Â¦¤òÊñ¤à³°³Ì¤«¤éÀ®¤êΩ¤Ã¤Æ¤¤¤Þ¤¹¡£HCV¥³¥¢¹³¸¶¸¡ºº¤Ï¡¢C·¿´Î±ê¥¦¥¤¥ë¥¹(HCV)¤Î¥³¥¢Éôʬ¤Î¥¿¥ó¥Ñ¥¯¤òľÀܸ¡½Ð¤·¤Þ¤¹¡£°ìÊý¡¢³Ë»ÀÁýÉý¸¡ºº¤Ï¡¢¥¦¥¤¥ë¥¹¤ò¹½À®¤¹¤ë³Ë»À¤Î°ìÉô¤òÌó1²¯ÇܤËÁýÉý¤·¤Æ¥¦¥¤¥ë¥¹¤ÎÍ̵¤ò¸¡½Ð¤·¤Þ¤¹¡£
¤Ç¤¹¤Î¤Ç¡¢
1¡¥HCV¹³Âθ¡ºº¤Ç¹âÎϲÁ¢ª´¶À÷¤Î²ÄǽÀ¤¬¹â¤¤¡£
2. HCV¹³Âθ¡ºº¤ÇÃæÎϲÁ¢ªHCV¹³¸¶¸¡ºº¢ªÍÛÀ¤Ê¤é´¶À÷¤Î²ÄǽÀ¤¬¹â¤¤¡£
3¡¥HCV¹³Âθ¡ºº¤ÇÄãÎϲÁ¢ªHCV¹³¸¶¸¡ºº¤Ç±¢À¢ªHCV³Ë»ÀÁýÉý¸¡ºº¢ªÍÛÀ¤Ê¤é´¶À÷¤Î²ÄǽÀ¤¬¹â¤¤¡£
4.HCV¹³Âθ¡ºº¤Ç±¢À¢ªHCV¤Ë´¶À÷¤·¤Æ¤¤¤Ê¤¤²ÄǽÀ¤¬¹â¤¤
¤È¤¤¤Ã¤¿¤³¤È¤¬¸¡ºº¤Çʬ¤«¤ê¤Þ¤¹¡£
À§Èó¤È¤âÈï³²¼ÔµßºÑ¤Î¤¿¤á¤Ë¡¢¼Â¸½²½¤·¤ÆÍߤ·¤¤¤È»×¤ï¤ì¤Þ¤¹¡£
¡Ú´ØÏ¢µ»ö¡Û
HCV¤Ë¤è¤ëËýÀ´Î±ê¤¬´Î¡¤¬¤ó¤Ë¿Ê¹Ô¤¹¤ë»ÅÁȤߤò²òÌÀ
Éã¿Æ¤Î°é»ù¤¬Áý¤¨¤Æ¡¢B·¿´Î±ê¤ÎÉã»Ò´¶À÷¤¬Áý²Ã